TABLE OF CONTENTS

8

 

Welcoming letter  from William T. McGivney, PhD, NCCN’s Chief Executive Officer

10

 

Roundtable: e-Health: educating, enlightening, or exasperating the American patient with cancer?

12

 

Roundtable: Clinical and policy decisions: comparative effectiveness, cost, and cost-effectiveness

16

 

Roundtable: The mTOR pathway as a new target

17

 

Oral chemotherapy: Here to stay, but questions remain

19

 

Oral mucositis is often underrecognized and undertreated

23

 

Breast cancer: Predictive biomarkers in breast cancer treatment

24

 

Breast cancer: NCCN guidelines for breast cancer are updated

28

 

Breast cancer: Cardiac toxicity in the treatment of breast cancer

29

 

Breast cancer: Treatment of breast cancer in older women

31

 

Colorectal cancer guidelines stress resectability of metastatic lesions in selected patients

33

 

Non-small cell lung cancer: Highlights of updated guidelines

35

 

Non-small cell lung cancer: Innovative agents are improving outcomes in NSCLC

37

 

Small cell lung cancer: New therapies needed for small cell lung cancer

41

 

Kidney cancer: Update on kidney cancer guidelines

42

 

Renal cell carcinoma: Issues in sequencing drugs for metastatic renal cell cancer

43

 

Tyrosine kinase inhibitors: Management of toxicity due to tyrosine kinase inhibitors

44

 

Prostate cancer guidelines: More emphasis on expectant management and life-expectancy estimation

47

 

Non-Hodgkin’s lymphoma: Updated guidelines for NHL: focus on follicular, mantle cell, and diffuse large B-cell lymphomas

50

 

Mycosis fungoides and Sézary syndrome: Treatment options expand for mycosis fungoides and Sézary syndrome

51

 

Chronic myelogenous leukemia: Update on treatment guidelines for CML

52

 

Multiple myeloma: Novel therapies are yielding better outcomes in multiple myeloma

54

 

Hepatocellular carcinoma: New interventional and systemic treatments are changing the outlook for patients with hepatocellular carcinoma

Copyright © 2008 by the National Comprehensive Cancer Network. All rights reserved. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without written permission from the NCCN.

The treatment algorithms discussed in the NCCN 13th Annual Conference Highlights (NCCN Highlights) are a statement of consensus of the panel members regarding their views of currently accepted approaches to treatment. Any clinician seeking to apply or consult these guidelines is expected to use independent medical judgment in the context of individual circumstances to determine any patient’s care or treatment. The reports of presentations included herein are based on the work of the presenters listed. Furthermore, the reader is advised that, except where specifically stated, all of the ideas and opinions expressed in the NCCN Highlights are the presenters’ own and do not necessarily reflect those of the NCCN, the member organizations, the editor, or the publisher. Publication of an advertisement or other product mention in the NCCN Highlights should not be construed as an endorsement of the product or manufacturer’s claims.

The information contained in the NCCN Highlights is presented for the purpose of educating our readership on cancer treatment and management. The information should not be relied on as complete or accurate, nor should it be relied on to suggest a course of treatment for a particular individual. It should not be used in place of a visit, call, consultation, or the advice of a licensed physician or other qualified health care provider. Patients with health care-related questions or concerns are advised to contact a physician or other qualified health care provider promptly.

Although every attempt has been made to verify that information presented within is complete and accurate, the information is provided “AS IS” without warranty, express or implied. The NCCN hereby excludes all implied warranties of merchantability and fitness for a particular use or purpose with respect to the information. Furthermore, the NCCN makes no warranty as to the reliability, accuracy, timeliness, usefulness, adequacy, completeness, or suitability of the information.

Discussions, views, opinions, and recommendations as to medical procedures, products, choice of drugs, and drug dosages are the responsibility of the authors or advertisers. No responsibility is assumed by the Publisher, Editor, or Editorial Board for any injury and/or damage to persons or property as a matter of product liability, negligence, or otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the material herein. Because of rapid advances in the medical sciences, independent verification of diagnoses and drug dosages should be made.